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M9550792.TXT
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1995-03-25
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Document 0792
DOCN M9550792
TI [African histoplasmosis: clinical and therapeutic aspects, relation to
AIDS. Apropos of 4 cases, including a case with HIV-1-HTLV-1
co-infection]
DT 9505
AU Geffray L; Veyssier P; Cevallos R; Beaud B; Mayolle J; Nogier C; Ray E;
Thouvenot D; Service de Medecine Interne et Maladies Infectieuses,
Centre; Hospitalier de Compiegne, Compiegne.
SO Ann Med Interne (Paris). 1994;145(6):424-8. Unique Identifier : AIDSLINE
MED/95168732
AB The authors report 4 cases of African histoplasmosis in Zairans. The
diagnostic was based ou cutaneous (4 patients), bones (3), lymph-nodes
(2), and bowel-localizations (1) and was confirmed by the presence of
Histoplasma duboisiis yeasts in cutaneous biopsy (4 patients), in pus of
abscess or cutaneous lesions (3) and in stools (1). Two HIV
seronegatives patients had a good outcome with amphotericin B. One
patient died without any treatment. One HIV-1 and HTLV-1 seropositive
patient had successful short-term outcome with ketoconazole. Seven
others cases of association between African histoplasmosis and AIDS are
noted in the literature. They suggest the opportunistic nature of this
deep mycosis.
DE Acquired Immunodeficiency Syndrome/*COMPLICATIONS/MICROBIOLOGY Adult
*AIDS-Related Opportunistic Infections Case Report English Abstract
Female *Histoplasmosis/DIAGNOSIS/THERAPY Human HIV
Infections/COMPLICATIONS/MICROBIOLOGY *HIV-1 *HTLV-I
Infections/COMPLICATIONS Male Zaire JOURNAL ARTICLE REVIEW REVIEW
OF REPORTED CASES
SOURCE: National Library of Medicine. NOTICE: This material may be
protected by Copyright Law (Title 17, U.S.Code).